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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPS6 All Species: 39.94
Human Site: S246 Identified Species: 62.76
UniProt: P62753 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62753 NP_001001.2 249 28681 S246 A S T S K S E S S Q K _ _ _ _
Chimpanzee Pan troglodytes XP_001147795 323 36940 S320 A S T S K S E S S Q K _ _ _ _
Rhesus Macaque Macaca mulatta XP_001109154 222 25518
Dog Lupus familis XP_533921 249 28564 S246 A S T S K S E S S Q K _ _ _ _
Cat Felis silvestris
Mouse Mus musculus NP_033122 249 28662 S246 A S T S K S E S S Q K _ _ _ _
Rat Rattus norvegicus P62755 249 28662 S246 A S T S K S E S S Q K _ _ _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506325 213 24331
Chicken Gallus gallus P47838 249 28636 S246 A S T S K S E S S Q K _ _ _ _
Frog Xenopus laevis P39017 249 28658 S246 A S T S K S E S S Q K _ _ _ _
Zebra Danio Brachydanio rerio NP_001003728 249 28690 S246 A S T S K S E S S Q K _ _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29327 248 28389 S245 E S K S S V S S D K K _ _ _ _
Honey Bee Apis mellifera XP_001120419 251 28877 S245 D S K S S S Q S A P T T Q K _
Nematode Worm Caenorhab. elegans Q9NEN6 246 28117 T243 S E S E V K K T S K K _ _ _ _
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P51430 249 28143 S241 K K R S R L S S A P A K P V A
Baker's Yeast Sacchar. cerevisiae P02365 236 26978
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.9 88.3 98.8 N.A. 100 100 N.A. 82.3 97.9 96.3 95.5 N.A. 75 76 59.4 N.A.
Protein Similarity: 100 74.9 89.1 99.1 N.A. 100 100 N.A. 83.9 99.5 98.3 97.9 N.A. 85.9 88 76.3 N.A.
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 0 100 100 100 N.A. 36.3 28.5 18.1 N.A.
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 0 100 100 100 N.A. 45.4 42.8 63.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 63.8 60.6 N.A.
Protein Similarity: N.A. N.A. N.A. 78.3 76.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 54 0 0 0 0 0 0 0 14 0 7 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % D
% Glu: 7 7 0 7 0 0 54 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 7 14 0 54 7 7 0 0 14 67 7 0 7 0 % K
% Leu: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 14 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 7 0 0 54 0 0 7 0 0 % Q
% Arg: 0 0 7 0 7 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 67 7 74 14 60 14 74 60 0 0 0 0 0 0 % S
% Thr: 0 0 54 0 0 0 0 7 0 0 7 7 0 0 0 % T
% Val: 0 0 0 0 7 7 0 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 67 67 67 74 % _